General method for generation of 3-siloxyallylmetallic species and their synthetic application

On treatment with vinylmagnesium bromide, most of the 伪-branched acyltrimethylsilanes initially form the corresponding 1-(trimethylsilyl)allylic alkoxides...

J Enda，I Kuwajima - 《Journal of the American Chemical Society》

Syntheses of Polycyclic Natural Products Employing the Intramolecular Double Michael Reaction

methods: in the first the substrate is treated with lithium hexamethyldisilazide, in the second with chlorotrimethylsilane, triethylamine, and zinc chloride ...

M Ihara，K Fukumoto - 《Angewandte Chemie International Edition》

A 5'-(trifluoromethyl)anthracycline glycoside: synthesis of antitumor-active 7-O-(2,6-dideoxy-6,6,6-trifluoro-alpha-L-lyxo-hexopyranosyl) adriamycinone.

7-O-(2,6-Dideoxy-6,6,6-trifluoro-alpha-L-lyxo-hexopyranosyl)adriam ycinone (3), whose substituent at C-5' is a lipophilic trifluoromethyl group, has been p...

Y Takagi，K Nakai，T Tsuchiya，... - 《Journal of Medicinal Chemistry》

Reagents and synthetic methods 55. New methods for the preparation of t-butyldimethylsilyl triflate and trimethylsilyl triflate

An expeditious synthesis of t-butyldimethylsilyl triflate is described from triflic acid and t-butyldimethylsilane. Reaction between trichloromethyltrimethylsilane and triflic acid is also reported.

JM Aizpurua，C Palomo - 《Tetrahedron Letters》

Synthetic applications of chromium(VI) reagents in combination with chlorotrimethylsilane

The synthetic utility of chromium(VI) reagents together with chlorotrimethylsilane, as new oxidizing systems, is described. Pyridinium dichromate (PDC) in ...

FP Cossfo，JM Aizpurua，C Palomo - 《Canadian Journal of Chemistry》

Novel Reactions of Ethylene Acetals with Silyl-Substituted Nucleophiles. A Mild and Efficient Procedure for the Synthesis of Homoallyl Alkyl Ethers and Uns...

Efficient one-pot synthesis of homoallyl alkyl ethers and dialkyl ethers was performed by the allylation and reduction of ethylene acetals with allyltrimet...

TS&T Oriyama - 《Synthetic Communications》

Silylated carbon nanotubes and methods of making same

hexamethyldisilazane (HMDS); chlorotrimethylsilane (TMCS); trichloromethylsilane (TCMS); an alkyl(alkylamino)silane; a tri(alkoxy)silane; tert-butyldimethylsilane; monochloroaminosilane; dichloroaminosilane; trichloroaminosilane; and dimethylamino...

Wong，S Stanislaus - US

One-pot synthesis of .ALPHA.-mono- and .ALPHA.,.ALPHA.-disubstituted cyclic ethers from lactones.

α-Mono- and α,α,-disubstituted cyclic ethers are prepared in good yields by the successive treatment of lactones with t-butyldimethylsiloxy-1-ethoxyethene and silyl nucleophiles (triethylsilane, allyltrimethylsilane, trimethylsilyl cy...

T Mukaiyama，K Homma，H Takenoshita - 《Chemistry Letters》

Reaction of 4',5'-epoxynucleosides with carbon nucleophiles: stereoselective synthesis of 4'-C-carbon-substituted nucleosides.

4',5'-Epoxythymidine (4) was obtained as a single diastereoisomer by oxidation of 3'-O-(t-butyldimethylsilyl)-4',5'-dehydrothymidine (3) with dimethyldioxirane. When the epoxide 4 was treated with allyltrimethylsilane in the presence of ...

K Haraguchi，S Takeda，H Tanaka - 《Nucleic Acids Research Supplement》