Ketamine sequelae. Evaluation of the ability of various premedicants to attenuate its psychic actions
摘要：
The ability of a number of drugs to abolish the emergence delirium and unpleasant dreams which follow anaesthesia induced with 2 mg/kg ketamine was studied. These included three benzodiazepines, droperidol and 'neurolept' combinations and four commonly-used premedicants. When given intravenously 10 min before induction of anaesthesia flunitrazepam and lorazepam gave best results. In a subsequent study, these two benzodiazepines and diazepam were given intravenously 30-40 min before induction of anaesthesia. There was no doubt that 4 mg lorazepam gave the greatest protection and is worthy of further study in this respect.
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关键词：
Humans Delirium Ketamine Analgesics, Opioid Hypnotics and Sedatives Tranquilizing Agents Anesthesia, Intravenous Preanesthetic Medication Time Factors Female
DOI：
10.1111/j.1365-2044.1978.tb12412.x
被引量：
年份：
2010
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