摘要：

Presents research which showed that a pyridine derivative Y-27632 selectively inhibits smooth-muscle contraction by inhibiting Ca2+ sensitization. Abnormal smooth-muscle contractility; Regulation of smooth-muscle contraction; Role of small GTPase Rho and Rho-associated kinase; Y-27632 target a Rho-associated protein kinase, p160ROCK7; Role of p160ROCK-mediated Ca2+ sensitization in pathophysiology of hypertension. INSET: Methods..

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