摘要：

thetic poly(dA-dT). (OP)&u+ readily cleaves supercoiled SV- 40 DNA to produce nicked circles (Fig. 3). The failure of the cuprous complex of 2,2'-bipyridine, 2,2',2"-terpyridine, or 2,9- dimethyl-l,lO-phenanthrolineto cleave the DNA further em- phasizes the unusual reactivity of OP.Involvement of Oxygen in the DNA Cleavage Reaction- Molecular oxygen, which plays a central role in the bleomycin- mediated cleavage of DNA, was also discovered to be an

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