Dissolution controlled active agent dispenser
申请(专利)号:
US06/150966
申请日期:
19800519
公开/公告号:
US04314557A
公开/公告日期:
19820209
申请(专利权)人:
ALZA CORPORATION
被引量:
摘要:
Drug dispensers comprising a flat body composed of a drug solute phase dispersed in a continuous polymer matrix phase in which the release rate of drug from the body is substantially constant and is controlled by the rate at which the drug solute phase dissolves in the continuous polymer matrix phase. Such control and constancy are realized by establishing specific correlations between the diffusion coefficient, dissolution rate constant, and thickness of the body.
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