Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene.
摘要:
Investigates whether sindbis virus (SV) infection induces programmed cell death in non-neuronal cells, and if so, whether virus-induced programmed cell death can be blocked by transfection with bcl-2. Demonstration that SV infection of baby hamster kidney, mouse neuroblastoma and rat prostatic adenocarcinoma cells results in programmed cell death; Cellular bcl-2 oncogene expression's role in the establishment of persistent viral infection; More.
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1993
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1998
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