Aminomethyl Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease

阅读量:

24

申请(专利)号:

11/795190

申请日期:

2006年1月13日

公开/公告号:

US 20080139538 A1

公开/公告日期:

06/26/2008

被引量:

574

摘要:

The present invention is directed to aminomethyl compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

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