摘要：

Forty-five patients, undergoing laparoscopic cholecystectomy, were equally randomly divided into general anesthesia, epidural and epidural plus atropine group. The cardiovascular reaction during intraperitoneal CO2 insufflation was observed. The results show that blood pressure and heart rate were raised slightly during the intraperitoneal insufflation under general anesthesia. The severe vagal reflex was induced easily by the intraperitoneal insufflation under epidural blockade (T4-L1). The ordinary dose of atropine administered intravenously before pneumoperitoneum could not inhibit the vagal reflex completely, and could not prevent effectively blood pressure drop caused by the insufflation. Therefore, the monitoring and management should be intensified during pneumoperitoneum, and anesthetic method should be selected reasonably.

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