摘要：

The authors present an all-night polygraphic cooperative study on a new benzodiazepine: Flunitrazepam (Ro 5–4200). The drug was administered (alternatively with placebo) for at least 8 subsequent nights to 6 normal subjects and to 6 insomniacs. Ro 5–4200 significantly increased the total time and decreased the latency of sleep and the number of awakenings. No significant effects on sleep stages and no remarkable side effects were observed.Copyright 1974 S. Karger AG, Basel

展开