Oral ketamine premedication in children (placebo controlled double-blind study)
摘要：
Ketamine 36 mg kg1 given by mouth to paediatric patients for anaesthetic premedication was evaluated. Forty-three children, ages 29 years were randomly allocated to receive either ketamine (3 or 6 mg kg1) or placebo (cola 0.2 mL kg1). Oral use of ketamine made separation from the families easier, gave an increased level of sedation, made acceptance of mask application easier and improved the emotional state in the recovery phase. These improvements were present with ketamine 3 mg kg1 and 6 mg kg1 in comparison with the placebo. We conclude that 3 mg kg1 ketamine given by mouth to premedicate paediatric patients is as effective as 6 mg kg1 but has a decreased incidence of side effects such as nystagmus and vomiting.
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DOI：
10.1046/j.1365-2346.1996.00058.x
被引量：
年份：
2010
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