Steroidal Sapogenins. XXX. 1 Synthesis and Side Chain Degradation of 22a,5β-Spirostan-3α-ol-11-one Acetate

The chemical conversion of a ring C unsubstituted steroid ("diosgenin") to cortisone via intermediates of the desirable 5β ("normal") series is described. Δ7,9,(11)-22a,5β-Spirostadien-3α-ol acetate (I), obtainable from "diosgenin," ...

G. Rosenkranz，M. Velasco，Carl Djerassi，... - 《Journal of the American Chemical Society》

Reductions in organic chemistry

Preface to the First Edition Preface to the Second Edition Introduction Safety First Abbreviations and Proprietary Names CATEGORIES OF REDUCTIONS Catalytic...

M Hudlick - ELLIS HORWOOD LTD

ROS-Responsive Mitochondria-Targeting Blended Nanoparticles: Chemo- and Photodynamic Synergistic Therapy for Lung Cancer with On-Demand Drug Release upon I...

Mitochondria in cancer cells maintain a more negative membrane potential than normal cells. Mitochondria are the primary source of cellular reactive oxygen...

C Yue，Y Yang，C Zhang，... - 《Theranostics》

THIOPYRIMIDINE DERIVATIVES

1348289 Thiopyrimidine nucleotide derivatives MERCK PATENT GmbH 10 Aug 1971 [22 Aug 1970] 37535/71 Heading C2P [Also in Divisions A5 and C3] The invention comprises thiopyrimidine derivatives of the general formula in which R is B is the...

FARBER, PETER，SCHEIT, KARL-HEINZ - US

Iridium-Catalyzed Asymmetric Synthesis of Functionally Rich Molecules Enabled by (Phosphoramidite,Olefin) Ligands

intramolecularetherification, thioetherification and spiroketalization processes.The second section highlights the use of readily available carbonnucleophiles possessing sp, sp2, and sp3 hybridizationin a series of enantioselective carbon鈥揷arbon ...

SL Rössler，DA Petrone，EM Carreira - 《Accounts of Chemical Research》

Novel magnesium and zinc porphyrazines containing galactose moieties: Synthesis via click reaction and characterization

In this study, galactose conjugated new magnesium and zinc porphyrazines were synthesized by the cyclotetramerization reaction of 2,3-bis[1-(2,2,7,7-tetram...

Y Baygu，B Yldz，Nilg，... - 《Inorganic Chemistry Communications》

Constructing a four-input molecular keypad lock with a multi-stimuli-responsive phthalocyanine

A novel conjugate of a zinc(II) phthalocyanine with three 2,4-dinitrobenzenesulfonate (DNBS) substituents, a bis(ferrocenylethenyl) boron dipyrromethene (B...

SYY Ha，DKP Ng

On the Study of Various Reductions of 2-Benzoylcyclopentene-1-carboxylic Acid

It was found that the Clemmensen reduction of 2-benzoylcyclopentene-1-carboxylic acid () did not give rise to 2-benzylcyclopentene-1-carboxylic acid (), but to a mixture of - and -2-benzylcyclopentane-1-carboxylic acid (and ) contrary to...

K Ohkata，T Hanafusa - 《Bull.chem.soc.jpn》