Frajunolides E-K, briarane diterpenes from Junceella fragilis.

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阅读量:

33

作者:

C. LiawY ShenY. LinT. HwangY. KuoAT Khalil

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摘要:

Chemical investigation of the gorgonian octocoral , collected in Taiwan, resulted in the isolation of seven new briarane-type , frajunolides E-K (1-7), in addition to 14 known briaranes, praelolide, junceellin, junceellolides A-E, and K, 11a,20a--4-deacetoxyjunceelolide D, umbraculolide A, junceellonoid A, and juncins Y, Z, and ZI, as well as . The structures of 1-7 were determined by analysis of HRESIMS and 2D spectroscopic data. Cytotoxicity and in vitro anti-inflammatory activities of compounds 1-7 were also evaluated.

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DOI:

10.1021/np800126f

被引量:

97

年份:

2008

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