New derivatives of 2,4,6-triiodo-isophthalic acid, proceses for their synthesis and X-ray contrasting materials containing these
申请(专利)号:
06/173765
申请日期:
07/30/1980
公开/公告号:
US4348377
公开/公告日期:
09/07/1982
申请(专利权)人:
Bracco Industria Chimica S.p.A. (Milan, IT)
被引量:
摘要:
Novel, radio-opaque compounds comprising water-soluble bis-[N-{3,5-bis-(hydroxyalkylaminocarbonyl)-2,4,6-triiodo-phenyl}-N-(.alph a.-hydroxyacyl)-amino]-alkanes are disclosed for use as X-ray contrast agents. These compounds are relatively simple to synthesize, possess low toxicity and have good stability as well as resistance to hydrolysis. Methods for preparation and use of the compounds are also disclosed.
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