摘要：

Significance The authors report a highly diastereoselective and enantioselective reaction of N-Boc-imines 1 with nitroalkanes 2 in the presence of catalyst 3. Aromatic, heteroaromatic and aliphatic imines were converted into the corresponding products 4 in excellent yields (88-99%) and outstanding enantioselectivities (er = 98:2 up to 99.5:0.5) for the highly favored anti-diastereo­mer (dr = 93:7 to 99:1). The free NH group of the sulfonamide functionality turned out to be essential for the performance of the multi-hydrogen-bonding catalyst.

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