Advance in biocatalytic synthesis of statin intermediates

阅读量:

32

作者:

XU Wei-ZhuoY ZhangLL LaiMA Xiao-NanLN ZhouS You

展开

摘要:

Statins are major type of cholesterol-lowing drugs,in which the(3R,5S)-dihydroxy esters are key structure and important intermediates for the function and production of statins.Bearing two chiral carbon atoms,the production of(3R,5S)-dihydroxy esters may be the rate-limiting steps in the statins manufacture.In this paper,the species,mechanisms,structures and synthetic routes of statins were summarized.Several biocatalystic routes for production of(3R,5S)-dihydroxy esters were also reviewed.

展开

被引量:

3

年份:

2012

通过文献互助平台发起求助,成功后即可免费获取论文全文。

相似文献

参考文献

引证文献

辅助模式

0

引用

文献可以批量引用啦~
欢迎点我试用!

引用