摘要：

The transamination reaction of thiazole moiety of thiamine (PyTh) by aromatic amine (A) in the presence of bisulfite (S) was studied kinetically. The reaction between PyTh and A was found to be second order with respect to PyTh and A, whereas the concentration of S was independent to the reaction rate. The reaction rate was linearly correlated to the pKa value of A. The transamination product (PyA) was also degradated by S in second order as well as PyTh. The complexation between PyTh and A was also investigated as a possible proceeding process of the transamination reaction.

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