A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
摘要:
Reports that the characterization of RANK (receptor activator of NF-kB), a member of the tumor necrosis factor receptor (TNFR) family derived from dendritic cells and the isolation of a RANK ligand (RANKL) by direct expression screening. The importance of dendritic cells, rare haemotopoietic cells that reside in a number of organs and tissues; The suggestion that RANK and RANKL seem to be important regulators of interactions between T cells and dentritic cells; Methods.
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年份:
1997
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