Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive caret.
摘要:
Mean dexmedetomidine pharmacokinetic variables seen in postoperative, intensive care patients were similar to those previously found in volunteers, with the exception of the steady-state volume of distribution. A small loading dose provided effective sedation with no adverse events.
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关键词:
Humans Dexmedetomidine Adrenergic alpha-Agonists Hypnotics and Sedatives Respiration, Artificial Intensive Care Postoperative Care Conscious Sedation Respiration Adult
DOI:
10.1093/bja/88.5.669
被引量:
年份:
2002
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