A PRODUCTION PROCESS FOR 16-DEHYDROPREGNENONEOL AND ITS ANALOGS
申请(专利)号:
PCT/CN2004/000636
申请日期:
Jun 14, 2004
公开/公告号:
WO 2005007668 A1
申请(专利权)人:
国省代号:
WO
被引量:
摘要:
A production process for 16-dehydropregnenoneol and its analogs is provided. In which, the psudosapogenin decomposed from steroid sapogenin, with or without purification, reacts with hydrogen peroxide in the organic solvent under the presence of metal catalysts and acid. The crude react product is directly subjected to alkali elimination hydrolysis and results in 16-dehydropregnenoneol or its analogs and 4R(or S)-methy1-4-hydroxyl-pentanoate. This process enhanced the availability of steroid sapogenin, avoided the contamination of the metal chromic compound consisted in the prior arts, and further enhanced the yield and is more suitable for production requirements.
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