The Fate of Circulating Tumor Cells I. Passage of Cells through Capillaries
摘要:
Experiments were done to study the behavior of circulating tumor cells as they engage the lumen of capillaries. The transplantable Vcarcinoma and Brown-Pearce carcinoma were used in domestic rabbits. Suspensions of cells were injected into the mesenteric artery while, simultaneously, microcinematic studies were made in the region of the arterio-capillary junctions of the mesentery. The majority of the cells from each tumor passed through the capillaries into the venous circulation. Cells of the Vcarcinoma were arrested more frequently than those of the Brown-Pearce carcinoma.
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1961
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