Genetically Modified Organisms for Increased Microbial Production of 3-Hydroxypropionic Acid Involving an Oxaloacetate alpha-decarboxylase
申请(专利)号:
US20100891760
申请日期:
2010-09-27
公开/公告号:
US8809027B1
公开/公告日期:
2014-08-19
申请(专利权)人:
MICHAEL D LYNCH;CHRISTOPHER P. MERCOGLIANO
摘要:
Microorganism compositions are described that comprise combinations of genetic modifications that include a genetic modification to increase oxaloacetate alpha-decarboxylase enzymatic activity. By such genetic modification a 3-hydroxypropionic acid ("3-HP") production pathway is provided or improved. In various embodiments, comprising other genetic modifications, including selected gene disruptions, 3-HP production is greater than in a control microorganism lacking such combinations of genetic modifications
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