A Toll-like receptor recognizes bacterial DNA.
摘要：
Shows that cellular response to unmethylated CpG dinucleotides in bacterial DNA is mediated by a Toll-like receptor, TLR9. Responses of TLR9-deficient mice to CpG DNA; Conclusion that vertebrate immune systems have evolved a specific Toll-like receptor that distinguishes bacterial DNA from self-DNA.
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2000
Nature
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