Novel synthesis of naphtho[2,1-b]pyrano pyrrolizidines and indolizidines through intramolecular 1,3-dipolar cycloaddition reaction
摘要：
A facile synthesis of a series of naphtho[2,1-b]pyrano pyrrolizidines and indolizidines was accomplished in good yields in a one-pot reaction through intramolecular 1,3-dipolar cycloaddition of azomethine ylides with Baylis–Hillman adducts as dipolarophiles. The protocol is applicable to a wide variety of photochromic and biologically active napthopyrano products. The regio and stereochemical outcome of the cycloaddition reaction was ascertained by X-ray crystallographic study of some of the products.
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DOI：
10.1016/j.tetlet.2010.04.017
被引量：
年份：
2010
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