摘要：

Bis(chloromethyl) ether (BCME) and chloromethyl methyl ether (CMME) are used in the textile industry and in the manufacture of dyestuffs and insecticides on account of their alkylating effects. Animal experiments (skin application, subcutaneous injection, inhalation) showed the carcinogenicity of these substances. This article reviews 60 cases of lung carcinoma in workers with an average of 7.4 years of more or less intensive exposure to BCME or CMME. Significantly, the mean age of decease was 45 years. The carcinogenic effect of CMME was much less than that of BCME.

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