Open Mass Spectrometry Search Algorithm
摘要：
Large numbers of MS/MS peptide spectra generated in proteomics experiments require efficient,sensitive and specific algorithms for peptide identification.In the Open Mass Spectrometry Search Algorithm(OMSSA),specificity is calculated by a classic probability score using an explicit model for matching experimental spectra to sequences.At default thresholds,OMSSA matches more spectra from a standard protein cocktail than a comparable algorithm.OMSSA is designed to be faster than published algorithms in searching large MS/MS datasets.
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关键词：
protein identification algorithm bioinformatics mass Spectrometry proteomics significance testing
DOI：
10.1016/j.gie.2007.11.009
被引量：
年份：
2004
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