The Spike-Timing Dependence of Plasticity
摘要：
In spike-timing-dependent plasticity (STDP), the order and precise temporal interval between presynaptic and postsynaptic spikes determine the sign and magnitude of long-term potentiation (LTP) or depression (LTD). STDP is widely utilized in models of circuit-level plasticity, development, and learning. However, spike timing is just one of several factors (including firing rate, synaptic cooperativity, and depolarization) that govern plasticity induction, and its relative importance varies across synapses and activity regimes. This review summarizes this broader view of plasticity, including the forms and cellular mechanisms for the spike-timing dependence of plasticity, and, the evidence that spike timing is an important determinant of plasticity invivo.
展开
关键词：
Animals Humans Synapses Neurons Dendrites Neurotransmitter Agents Neuronal Plasticity Action Potentials Models, Neurological Time Factors
DOI：
10.1016/j.neuron.2012.08.001
被引量：
年份：
2012
Elsevier
Elsevier
(全网免费下载)
国家科技图书文献中心
(权威机构)
Semantic Scholar
(全网免费下载)
掌桥科研
查看更多
Semantic Scholar
万方医学
dx.doi.org
Europe PMC
(全网免费下载)
Europe PMC
Cell Press
NCBI
(全网免费下载)
NCBI
NCBI
ProQuest
ResearchGate
EBSCO
学术范
mysciencework.com
en.zl50.com
core.ac.uk
(全网免费下载)
capocaccia.ethz.ch
(全网免费下载)
onAcademic
infona.pl
jn.physiology.org
mendeley.com
pubfacts.com
pubget.com
rstb.royalsocietypublishing.org
www.socolar.com
学术范
(全网免费下载)
Elsevier
(全网免费下载)
Semantic Scholar
(全网免费下载)
Europe PMC
(全网免费下载)
NCBI
(全网免费下载)
capocaccia.ethz.ch
(全网免费下载)
学术范
(全网免费下载)
core.ac.uk
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
来源期刊
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
