Organic Solvent–Free Direct Asymmetric Aldol Reactions Catalyzed by a Siloxy Serine Organocatalyst in Brine
摘要:
A siloxy serine organocatalyst has been developed to catalyze direct asymmetric aldol reactions in aqueous saline media. The asymmetric aldol reactions between a selection of aromatic aldehydes and cyclohexanone afforded the products in good yields and enantioselectivities (up to 92% ee).
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DOI:
10.1080/00397910902730937
被引量:
年份:
2009
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