Hydrogen Peroxide Scavenging Activity of Novel Coumarins Synthesized Using Different Approaches
摘要：
New derivatives of 7-hydroxy-4-methylcoumarin were synthesized using a chemical method and a microwave-assisted method to compare the feasibility, reaction times, and yields of the product. The newly synthesized coumarins were characterized by different spectroscopic techniques (FT-IR and NMR) and micro-elemental analysis (CHNS). In vitro antioxidant activities of these compounds were evaluated against hydrogen peroxide and were compared with standard natural antioxidant, vitamin C. Our results reveal that these compounds exhibit excellent radical scavenging activities.
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关键词：
HYDROGEN peroxide PRECIPITATION scavenging HETEROCYCLIC compounds synthesis COUMARINS FOURIER transform infrared spectroscopy RADICALS (Chemistry)
DOI：
10.1371/journal.pone.0132175
被引量：
年份：
2015
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