Benzimidazoles and analogs thereof as antivirals

阅读量:

438

申请(专利)号:

12/620307

申请日期:

11/17/2009

公开/公告号:

US8207173

公开/公告日期:

06/26/2012

发明人:

PP SethEA JeffersonRH GriffeyEE Swayze

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被引量:

6

摘要:

Provided are compounds of the formula: wherein R N1 is a substituent of formula G 1 -NX 1 X 2 , wherein G 1 is an optionally further substituted alkylene, which optionally forms, together with R N2 , a cyclic group, and each of X 1 and X 2 is independently H or an N-substituent, or X 1 and X 2 together form a heterocyclic ring, or X 1 together with G 1 forms a cyclic group and X 2 is H or an N-substituent; and each of Z 1 , Z 2 , Z 3 and Z 4 is H or a substituent, or two of Z 1 , Z 2 , Z 3 and Z 4 together form an optionally substituted ring, and further wherein at least one of Z 1 , Z 2 , Z 3 and Z 4 is other than H, and salts thereof, pharmaceutical compositions and methods of using the compounds. The compounds have antiviral activity.

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2012
被引量:2

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