METHODS AND SUBSTANCES FOR STIMULATING MUSCLE REGENERATION

阅读量:

16

申请(专利)号:

US13058581

申请日期:

20090813

公开/公告号:

US20110313027A1

公开/公告日期:

20111222

申请(专利权)人:

Ernö Zádor

发明人:

Ern Zádor

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被引量:

1

摘要:

The invention is concerned with the field of muscle growth and regeneration. More particularly, the invention provides novel methods, substances and uses for facilitating the growth or regeneration of skeletal muscles. The methods, uses and substances of the invention are useful in the treatment or prevention of degenerative-regenerative muscular disorders or in the treatment of muscle injuries. The substances provided by the invention are capable of upregulating the calcineurin-NFAT-IL-4, advantageously by inhibiting the activity of the Ras or SERCA1b gene product. Introduction of the substances provided by the invention into only a small percentage of the fibers present in a regenerating muscle facilitates the regeneration of the whole muscle concerned.

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