Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus
摘要：
A normal human gene homologous to the p21 ras oncogene of Harvey murine sarcoma virus induced oncogenic transformation and high p21 ras levels in murine fibroblasts when this gene was ligated to a control element (the long terminal repeat) from a murine or feline retrovirus. These results indicate that high levels of a gene product encoded by a normal human oncogene can induce tumorigenic transformation.
展开
关键词：
Cells, Cultured Cell Line Animals Humans Mice Rats Sarcoma Viruses, Murine Kirsten murine sarcoma virus Cell Transformation, Neoplastic DNA Restriction Enzymes
DOI：
10.1038/297479a0
被引量：
年份：
1982
Nature
Springer
Nature
(全网免费下载)
国家科技图书文献中心
(权威机构)
万方医学
查看更多
dx.doi.org
Europe PMC
NCBI
NCBI
AACR
adsabs.harvard.edu
ResearchGate
ResearchGate
(全网免费下载)
ProQuest
EBSCO
mcponline.org
ftp.palgrave-journals.com
mcb.asm.org
pubfacts.com
gastrojournal.org
journal-of-hepatology.eu
readcube.com
onAcademic
钛学术
(全网免费下载)
钛学术
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
来源期刊
引用走势
站内活动
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
