Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
摘要：
Using their senses of taste and smell, animals recognize a wide variety of chemicals. The nematode C. elegans has only fourteen types of chemosensory neurons, but it responds to dozens of chemicals, because each chemosensory neuron detects several stimuli. Here we describe over 40 highly divergent members of the G protein-coupled receptor family that could contribute to this functional diversity. Most of these candidate receptor genes are in clusters of two to nine similar genes. Eleven of fourteen tested genes appear to be expressed in small subsets of chemosensory neurons. A single type of chemosensory neuron can potentially express at least four different receptor genes. Some of these genes might encode receptors for water-soluble attractants, repellents, and pheromones.
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关键词：
Animals Animals, Genetically Modified Caenorhabditis elegans Octanols Benzaldehydes Recombinant Fusion Proteins Receptors, Cell Surface Sequence Analysis, DNA Smell Behavior, Animal
DOI：
doi:10.1016/0092-8674(95)90162-0
被引量：
年份：
1995
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