Rab25 and CLIC3 Collaborate to Promote Integrin Recycling from Late Endosomes/Lysosomes and Drive Cancer Progression
摘要:
Activated integrins move from late endosomes/lysosomes to the plasma membrane Spatial segregation of pathways recycling active and inactive integrins CLIC3 regulates cell migration and invasion CLIC3 dictates whether Rab25 functions as cancer progression suppressor or promoter
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关键词:
Cells, Cultured Cell Membrane Endosomes Lysosomes Fibroblasts Dermis Animals Rabbits Humans Pancreatic Neoplasms
DOI:
10.1016/j.devcel.2011.11.008
被引量:
年份:
2012


















































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