Avian influenza virus (H5N1): a threat to human health.
摘要：
Pandemic influenza virus has its origins in avian influenza viruses. The highly pathogenic avian influenza virus subtype H5N1 is already panzootic in poultry, with attendant economic consequences. It continues to cross species barriers to infect humans and other mammals, often with fatal outcomes. Therefore, H5N1 virus has rightly received attention as a potential pandemic threat. However, it is noted that the pandemics of 1957 and 1968 did not arise from highly pathogenic influenza viruses, and the next pandemic may well arise from a low-pathogenicity virus. The rationale for particular concern about an H5N1 pandemic is not its inevitability but its potential severity. An H5N1 pandemic is an event of low probability but one of high human health impact and poses a predicament for public health. Here, we review the ecology and evolution of highly pathogenic avian influenza H5N1 viruses, assess the pandemic risk, and address aspects of human H5N1 disease in relation to its epidemiology, clinical presentation, pathogenesis, diagnosis, and management.
展开
关键词：
DOI：
10.1128/CMR.00037-06
被引量：
年份：
2007
Taylor & Francis
Wiley
万方医学
掌桥科研
Semantic Scholar
(全网免费下载)
查看更多
BioOne
Europe PMC
Pubmed Central
(全网免费下载)
Oxford Univ Press
Europe PMC
(全网免费下载)
NCBI
NRC Research Press
ResearchGate
(全网免费下载)
ResearchGate
Citeseer
Citeseer
(全网免费下载)
bvsalud.org
hal.cirad.fr
cmr.highwire.org
(全网免费下载)
hdl.handle.net
godlikeproductions.com
(全网免费下载)
pubfacts.com
ResearchGate
(全网免费下载)
mendeley.com
rstb.royalsocietypublishing.org
nejm.org
jimmunol.org
www.socolar.com
cmr.asm.org
SAGE
scienceopen.com
journal.9med.net
travelmedicinejournal.com
cmr.asm.org
(全网免费下载)
hal-riip.archives-ouvertes.fr
hkupasteur.hku.hk
(全网免费下载)
core.ac.uk
deepdyve.com
hub.hku.hk
journals.asm.org
Semantic Scholar
(全网免费下载)
Europe PMC
(全网免费下载)
Pubmed Central
(全网免费下载)
ResearchGate
(全网免费下载)
Citeseer
(全网免费下载)
cmr.asm.org
(全网免费下载)
cmr.highwire.org
(全网免费下载)
godlikeproductions.com
(全网免费下载)
hkupasteur.hku.hk
(全网免费下载)
ResearchGate
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
