Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants
申请(专利)号:
US07/991909
申请日期:
19921217
公开/公告号:
US05326552A
公开/公告日期:
19940705
申请(专利权)人:
STERLING WINTHROP INC.
被引量:
摘要:
The present invention is directed to a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.< P>The present invention is still further directed to a method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an X-ray an effective contrast producing amount of a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.
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