Missing Pieces in the NF-κB Puzzle
摘要：
The regulation of the transcription factor NF-κB activity occurs at several levels including controlled cytoplasmic-nuclear shuttling and modulation of its transcriptional activity. A critical component in NF-κB regulation is the IκB kinase (IKK) complex. This review is focused on recent progress as well as unanswered questions regarding the regulation and function of NF-κB and IKK.
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关键词：
Animals Humans Cell Nucleus Cytoplasm NF-kappa B Signal Transduction Catalytic Domain Active Transport, Cell Nucleus Gene Expression Regulation I-kappa B Kinase
DOI：
10.1016/S0092-8674(02)00703-1
被引量：
年份：
2002
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