摘要：

Our initial interest in the sulfoxide group arose from some photochemical investigations in this area. We subsequently turned our attention to the resolution of two important methodological problems in organic sulfur chemistry the reduction (deoxygenation) of sulfoxides to sulfides and, albeit somewhat less successfully, the reduction of sulfones to sulfides or sulfoxides. Currently, we have been exploring the application of a novel intramolecular silaPummerer reaction to the construction of ring D in the eudistomin series of alkaloids, several of which possess interesting antiviral and antitumor properties.

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