MicroRNA-155—at the Critical Interface of Innate and Adaptive Immunity in Arthritis
摘要：
MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a changing environment by modulating the cell transcriptome. miR-155 is a multifunctional miRNA enriched in cells of the immune system and is indispensable for the immune response. However, when deregulated, miR-155 contributes to the development of chronic inflammation, autoimmunity, cancer, and fibrosis. Herein, we review the evidence for the pathogenic role of miR-155 in driving aberrant activation of the immune system in rheumatoid arthritis, and its potential as a disease biomarker and therapeutic target.
展开
DOI：
10.3389/fimmu.2017.01932
被引量：
年份：
2017
Europe PMC
(全网免费下载)
NCBI
(全网免费下载)
frontiersin.org
(全网免费下载)
eprints.gla.ac.uk
(全网免费下载)
core.ac.uk
(全网免费下载)
publicatt.unicatt.it
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
引用走势
2018
被引量：10
站内活动
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
