In neural systems, information is often carried by ensembles of cells rather than by individual units. Optical indicators provide a powerful means to revea...
Rapid removal of glutamate from the extracellular space is required for the survival and normal function of neurons. Although glutamate transporters are ex...
Cultured astrocytes can release a variety of messenger substances via receptor-mediated mechanisms, implicating their potential for regulated exocytosis an...
The small GTP-binding protein Rab3a is involved in regulated secretory pathways and is enriched in synaptic and neuroendocrine secretory vesicles. We have ...
Endoplasmic reticular Ca stores, instrumental for intra- and intercellular calcium signalling, can be depleted by different receptor agonists. In the prese...
Apolipoprotein A-I (apoA-I) induces the translocation of newly synthesized cholesterol as well as caveolin-1 to the cytosolic lipid-protein particle (CLPP)...
Astrocytes were long referred to as passive cells in the central nervous system (CNS). However, the application of fluorescent Ca2+ indicators revealed the...
Measurement of fura-2 fluorescence in type I astrocytes from rat cerebral cortex showed that the intracellular calcium ion concentration undergoes very lar...
Astrocytic responses to activation of metabotropic glutamate receptors group I (mGluRs I) and alpha(1)-adrenoreceptors in cultured cells have been assessed...
