DEUTERIUM-ENRICHED NEBIVOLOL
The present application describes deuterium-enriched nebivolol, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
AW Czarnik
1H-imidazo[4,5- c ]quinolinone derivatives
The invention relates to the use of 1H-imidazo[4,5- c ]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment ...
P Furet，FS Kalthoff，R Mah，... - WO
Histone deacetylase inhibitors
This invention relates to generally inhibiting histone deacetylase ("HDAC") enzymes (e.g., HDAC1, HDAC2, and HDAC3) using compounds of formula (I), where...
V Jacques，James R Rusche，NP Peet，... - US
Substituted pyrazolopyridines, compositions containing them, method for the production thereof, and their use
The disclosure relates to substituted pyrazolo-pyridines, compositions containing them, methods for the production thereof, and to their use as medicaments, in particular, as anticancer agents.
B Ronan，M Tabart，F Halley，... - US
Benzoquinolizinium salt derivatives as anticancer agents
13-substituted 5,6-dihydrodibenzo[a,g]quinolizinium salt compounds of the general formula (I)
P Lombardi，F Buzzetti，AG Arcamone
Deuterium-enriched aztreonam
The present application describes deuterium-enriched aztreonam, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.
Czarnik, Anthony W
PHENYL-1,2,4-OXADIAZOLONE DERIVATIVES WITH PHENYL GROUP, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS
The invention relates to phenyl-1,2,4-oxadiazolone derivatives with phenyl group and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta agonist activity. What are described are compound...
P Bernardelli，S Keil，M Urmann，...
Treatment of hyperproliferative diseases
We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/...
S Ward，C Bavik，M Cork，... - US
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
Crystalline modifications of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol, pharmaceutical compositions which contain these modifications, and the use thereof to treat pain or other conditions.
M Gruss - US
Fibrillation-resistant insulin and insulin analogues
A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue t...
M Weiss - US
