A Concise Asymmetric Synthesis of (+)‐Muscarine from (S)‐γ‐Hydroxymethyl‐γ‐butyrolactone.
摘要:
A highly stereoselective synthesis of (+)-muscarine iodide has been achieved in eight steps and 20% overall yield from commercially available ()-γ-hydroxymethyl-γ-butyrolactone.Graphical abstract
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DOI:
10.1016/j.tetlet.2007.03.014
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年份:
2007
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