emb-5, a gene required for the correct timing of gut precursor cell division during gastrulation in Caenorhabditis elegans, encodes a protein similar to the yeast nuclear protein SPT6
摘要：
The emb-5 gene is required for the correct timing of division of gut precursor cells during gastrulation in Caenorhabditis elegans . We have now characterized the molecular structure of emb-5 . The predicted emb-5 -encoded protein (EMB-5) possesses an extremely acidic amino-terminus and overall similarity to the Saccharomyces cerevisiae nuclear protein SPT6, which has been shown to affect the transcription of a variety of genes and suggested to play a role in chromatin assembly or modification. EMB-5 may function in the control of cell cycle timing by modulating chromatin structure and consequently affects morphogenesis of C. elegans .
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DOI：
10.1007/BF00276929
被引量：
年份：
1993
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