New briaranes from the octocorals Briareum excavatum (Briareidae) and Junceella fragilis (Ellisellidae)
摘要:
Six 12-hydroxybriaranes, including four new diterpenoids, briaexcavatins I–L (–), and two known metabolites, excavatolides C () and E (), have been isolated from the cultured scleraxonia ). The structures of above compounds were determined by spectroscopic methods and the structures of and were further confirmed by X-ray data analysis for the first time. The absolute configuration of was elucidated by chemical conversion. Some of these briaranes have displayed inhibitory effects on superoxide anion generation by human neutrophils.Graphical abstract
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DOI:
10.1016/j.tet.2008.01.023
被引量:
年份:
2008
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