New briaranes from the octocorals Briareum excavatum (Briareidae) and Junceella fragilis (Ellisellidae)

来自 Elsevier

阅读量:

61

摘要:

Six 12-hydroxybriaranes, including four new diterpenoids, briaexcavatins I–L (–), and two known metabolites, excavatolides C () and E (), have been isolated from the cultured scleraxonia ). The structures of above compounds were determined by spectroscopic methods and the structures of and were further confirmed by X-ray data analysis for the first time. The absolute configuration of was elucidated by chemical conversion. Some of these briaranes have displayed inhibitory effects on superoxide anion generation by human neutrophils.Graphical abstract

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DOI:

10.1016/j.tet.2008.01.023

被引量:

103

年份:

2008

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Cheminform
2008

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