Water-Mediated Strecker Reaction: An Efficient and Environmentally Friendly Approach for the Synthesis of α-Aminonitrilesviaa Three-Component Condensation

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26

摘要:

The synthesis of α-aminonitriles by a direct three component Strecker reaction has been achieved in water, which is found to be an inexpensive, non-toxic and eco-friendly reaction medium for the nucleophilic addition. This protocol is effective to a wide variety of substrates with different functional groups and does not require the use any other catalyst.

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DOI:

10.1080/00397910903457381

被引量:

22

年份:

2010

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来源期刊

Synthetic Communications
2010年11月03日

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2010
被引量:8

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