System for the controlled-rate release of active substances

A system for the controlled-rate release of active substances, consisting of: (a) a deposit-core comprising the active substance and having defined geometric form; (b) a support-platform applied to said deposit-core. Said deposit-core co...

C Paolo，LM Aldo，C Ubaldo - EP

Diltiazem formulation

The present invention is directed to a diltiazem formulation suitable for one a day administration. The formulation contains a blend of diltiazem beads having two differing dissolution profiles.

EJ Geoghegan，S Mulligan，DE Panoz，... - US

Controlled ecological life support systems (CELSS) flight experimentation

The NASA CELSS program has the goal of developing life support systems for humans in space based on the use of higher plants. The program has supported res...

M Kliss，R Macelroy，B Borchers，... - 《Advances in Space Research the Official Journal of the Committee on Space Research》

Diltiazem formulation

The present invention is directed to a diltiazem formulation suitable for one a day administration. The formulation contains a blend of diltiazem beads having two differing dissolution profiles.

DL Hendrickson，CD Dan，MS Williams，...

Sustained release pharmaceutical composition of diltiazem

A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerizate...

H Stevens，M Chariot，F Arnold，... - US

4847077 Controlled release pharmaceutical preparations : Yegnaswam Raghunathan assigned to Pennwalt Corporation

A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerizate...

R Clyde，JA Collins，S Compton，... - 《General Pharmacology the Vascular System》

Pulsatile particles drug delivery system

Unit dosage form for delivering drugs into the body in a series of sequential, pulsatile releasing events employs conventional pharmaceutical equipment and processes for optimum economy, reliability, and bioavailability. The system can b...

CHEN CHIH-MING - US

Water-disintegratable capsule containing pellet populations which release drugs by bursting at different times after environmental contact, pellets contain...

Unit dosage form for delivering drugs into the body in a series of sequential, pulsatle releasing events employs conventional pharmaceutical equipment and ...

CM Chen - US

Multiparticulate pulsatile drug delivery system

A unit dosage form of capsule, tablet or the like is composed of a large number of pellets made up of two or more populations of pellets or particles. Each pellet contains a core containing the therapeutic drug and a water soluble osmot...

CM Chen - WO

Taste-masked pharmaceutical compositions

In accordance with the present invention, these and other objects are achieved by a pharmaceutical composition comprised of 1) a pharmaceutical core which is further comprised of a pharmaceutically active dose of a compound and, 2) a mic...

AM Mehta - WO