ChemInform Abstract: Diastereoselective Mukaiyama Aldol Reaction of (N-Alkyl) Isatins with 2-(Trimethylsilyloxy)furan by Using Lanthanum Triflate.

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29

摘要:

An efficient vinylogous Mukaiyama aldol reaction (VMAR) of 2-(trimethylsilyloxy)furan with various (-alkyl)isatins is described in the presence of lanthanum(III) triflates (5 mol %). The reaction proceeds rapidly and affords the corresponding 3-hydroxy-(5-oxo-2,5-dihydrofuran-2-yl)indolin-2-one in high yields with good diastereoselectivities (erythroGraphical abstract

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DOI:

10.1016/j.tet.2011.02.033

被引量:

16

年份:

2011

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