摘要：

Smoking is an important atherothrombotic risk factor, observed in one third of patients undergoing per-cutaneous coronary intervention (PCI) at our service. The objective of the present study was to analyze the clinical angiographic profile and the results of the procedure in this population. From January 2002 to October 2009, 5,466 PCI procedures were carried out, of which 1,745 in smokers and 3,721 in non-smokers. All data were prospectively obtained and patients were followed-up during hospitalization. In the group of smokers, there was prevalence of males (75.2% vs. 62.1%; P < 0.001), younger patients (56.4 years vs. 64.5 years; P < 0.001), acute myocardial infarction (AMI) with ST-segment elevation (37.5% vs. 19.5%; P < 0.001), single-vessel disease (56.5% vs. 47%; P < 0.001), long lesions (14.7% vs. 12%; P < 0.001), bifurcations (5.6% vs. 3.9%; P = 0.002), thrombotic lesions (15.4% vs. 9%; P < 0.001), total occlusions (18.2% vs. 11.2%; P < 0.001) and greater use of IIb/IIIa inhibitors (2.5% vs. 1.6%; P = 0.04). Clinical success (96.5% vs. 96.1%; P = 0.5) as well as the need of emergency surgical revascularization (0.06% vs. 0.05%; P = 0.22), AMI (0.74% vs. 1.02%; P = 0.32) or death (0.63% vs. 0.73%; P = 0.69) were similar in both groups. Smokers, however, showed a trend towards a greater number of strokes during hospitalization (0.11% vs. 0.05%; P = 0.07). Smokers undergoing coronary angioplasty are eight years younger than non-smokers, present AMI with ST-segment elevation more frequently and have greater angiographic complexity. The use of modern technological resources allowed comparable in-hospital results, with the exception of stroke, whose incidence tends to be twice as high in smokers.

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