Synthesis and antimicrobial activities of novel naphtho[2,1-b]pyran, pyrano[2,3-d]pyrimidine and pyrano[3,2-e][1,2,4]triazolo[2,3-c]-pyrimidine derivatives - ScienceDirect
摘要:
The synthesis of new naphtho[1′,2′:5,6]pyrano[2,3- d ]pyrimidines and related heterocycles has been reported. The key intermediate 3-amino-8-bromo-1-( p -methoxyphenyl)-1 H -naphtho[2,1- b ] pyran-2-carbonitrile ( 3c ) was obtained in one pot synthesis by treating α-cyanocinnamonitrile ( 1c ) with 6-bromo-2-naphthol ( 2 ). Antimicrobial activity was shown for some of the synthesized compounds.
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DOI:
10.1016/S0014-827X(01)01168-5
被引量:
年份:
2001
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