Neurotrophin-Mediated Rapid Signaling in the Central Nervous System: Mechanisms and Functions
摘要:
Neurotrophins regulate growth, survival, and differentiation of central neurons. In addition to the "classical" effects that are relatively slow neurotrophins also elicit rapid signaling that modulates a variety of cellular functions such as membrane excitability, synaptic transmission, and activity-dependent synaptic plasticity. These rapid actions are mediated mainly through the interaction of Trk receptors with ion channels and ionotropic receptors in the plasma membrane.
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DOI:
10.1152/physiol.00042.2004
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年份:
2005



































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