Macrophages and Dendritic Cells Use Different Axl/Mertk/Tyro3 Receptors in Clearance of Apoptotic Cells
摘要：
The peritoneal cavity is recognized as an important site for autoreactive B cells prior to their transit to other immune tissues; however, little is known of the genes that may regulate this process. Mice lacking the receptor tyrosine kinase, Mertk, display a lupus-like autoimmune phenotype with splenomegaly and high autoantibodies titers. In this study, we investigate whether Mertk regulates...
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关键词：
Animals Mice Mice, Mutant Strains Dendritic Cells Macrophages Oncogene Proteins Proto-Oncogene Proteins Homeostasis Dimerization Phosphorylation
DOI：
10.4049/jimmunol.178.9.5635
被引量：
年份：
2007
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